Home Publication

Paper List

Conference List

・2016

76. "Investigation og the Amelioration Effects of Oligonol® on Tinnitus in Randomized Double-blinded Placebo-controlled Trial"
Jun Nishihira (Hokkaido Information University, Japan), Japan Pharmacology & Therapeutics, 44(9): 1329-1336, 2016

75. "Anti-obesity effects of Oligonol in healthy subjects: a double blind, randomized placebo-controlled trial"
Masaki Taga (Wayo Women's University, Japan), Clinical Parmacology and Therapy, 26(3), 85-96, 2016

74. "Global Liver Gene Expression Analysis on a Murine Metabolic Syndrome Model Treated by Low-molecular-weight Lychee Fruit Polyphenol (Oligonol®)"
Koji Wakame (Hokkaido Pharmaceutical University School of Pharamacy, Japan), Anticancer Research, 36(7): 3705-3713, 2016

73. "Oligonol, a low-molecular-weight polyphenol derived from lychee fruit, protects the pancreas from apoptosis and proliferation via oxidative stress in streptozotocin-induced diabetic rats"
Chan Hum Park (National Institute of Horticultural, Korea), Food & Function, 7(7): 3056-3063, 2016

72. "Flavanol-rich lychee fruit extract alleviates diet-induced insulin resistance via suppressing mTOR/SREBP-1 mediated lipogenesis in liver and restoring insulin signaling in skeletal muscle"
Sue-Joan Chang (National Cheng Kung University, Taiwan), Molecular Nutrition & Food Research, 60(10): 2288-2296, 2016

71. "Oligonol, a lychee fruit-derived low-molecular form of polyphenol mixture, suppresses inflammatory cytokine production from human monocytes"
Insoo Kang (Yale University School of Medicine, USA), Human Immunology, 77(6): 512-525, 2016

70. "Low-molecular-weight polyphenols protect kidney damage through suppressing NF-κB and modulating mitochondrial biogenesis in diabetic db/db mice"
Sue-Joan Chang (National Cheng Kung University, Taiwan), Food & Function, 7(4): 1941-1949, 2016

69. "Oligonol promotes anti-aging pathways via modulation of SIRT1-AMPK-Autophagy Pathway"
Takako Yokozawa (Toyama University, Japan), Nutrition Research and Practice, 10(1): 3-10, 2016

68. "Oligonol Ameliorates CCl4-Induced Liver Injury in Rats via the NK-Kappa B and MAPK Signaling Pathways"
Jeonghyeon Bak (Pusan National University, Korea), Oxidative Medicine and Cellular Longevity, Article ID 3935841, 2016

67. "Inhibitory evaluation of oligonol on α-glucosidase, protein tyrosine phosphatase 1B, cholinesterase, and β-secretase 1 related to diabetes and Alzheimer's disease"
Takako Yokozawa (Toyama University, Japan), Archives of Pharmacal Research, 39(3), 409-420, 2016

・2015

66. "Inhibitory effects of several saturated fatty acids and their related fatty alcohols on the growth of Candida albicans"
Kazumi Hayama (Teikyo University Institute of Medical Mycology, Japan), Drug Discoveries & Therapeutics, 9(6): 386-390, 2015

65. "Development a new aroma candy for maintenance of the oral health"
Kazumi Hayama (Teikyo University Institute of Medical Mycology, Japan), Medical Mycology Research, 6(1): 3-9, 2015

64. "Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model"
Jae-Yeo Park (Yonsei University College of Nursing, Korea), BMC Complementary and Alternative Medicine, 15: 185, 2015

63. "Therapeutic Effects of Oligonol, Acupuncture, and Quantum Light Therapy in Chronic Nonbacterial Prostatitis"
Hakan Akdere (Trakya University, Turkey), Evidence-Based Complementary and Alternative Medicine, doi: org/10.1155/2015/687196, 2015

62. "Protective role of oligonol from oxidative stress-induced inflammation in C6 glial cell"
Eun Ju Cho (Pusan National University, Korea), Nutrition Research and Practice, 9(2):123-128, 2015

61. "Analgesic Effects of Oligonol, Acupuncture and Quantum Light Therapy on Chronic Nonbacterial Prostatitis"
Mehmet Burgazli (Wuppertal Research and Medical center, Germany), Iranian Red Crescent Medical Journal, 17(4): e26006, 2015

60. "The Effects of an Aroma Candy on Oral Candida albicans Colony-forming Units (CFU) and Oral Hygiene States in Healthy Elderly Carrying Candida albicans"
Motohumi Suzuki (Institute of Medical Mycology, Teikyo University, Japan), Medical Mycology Journal, 56: J31-J40, 2015

59. "Anti-Candida Activity of Aroma Candy and Its Protective Activity Against Murine Oral Candidasis"
Kazumi Hayama (Institute of Medical Mycology, Teikyo University, Japan), Medical Mycology Journal, 56: J23-J29, 2015

58. "Oligonol, a low-molecular-weight polyphenol derived from lychee fruit, attenuates gluco-lipotoxicity mediated renal disorder in type 2 diabetic db/db mice"
Chan Hum Park (University of Toyama, Japan), Drug Discoveries & Therapeutics, 9(1): 13-22, 2015

57. "Oligonol Supplementation Modulates Plasma Volume and Osmolality and Sweating After Heat Load in Humans."
Jeong Beom Lee (Soonchunhyang University, Korea), Journal of Medicinal Food, 18(5): 578-583, 2015

・2014

56. "Oligonol improves memory and cognition under an amyloid β25-35-induced Alzheimer's mouse model"
Yoon Young Choi (Pusan National University, Korea), Nutrition Research, 34: 595-603, 2014

55. "Beneficial effect of Oligonol supplementation on sweating response under heat stress in humans"
Jeong Beom Lee (Soonchunhyang University, Korea), Food & Function, 5(10): 2516-2520, 2014

54. "Inhibition of Adipogenesis by Oligonol through Akt-mTOR Inhibition in 3T3-L1 Adipocytes"
Hyangkyu Lee (Yonsei University College of Nursing, Korea), Evidence-Based Complementary and Alternative Medicine, doi: 10.1155/2014/895272, 2014

53. "The Anti-fatigue Effect of the Next Generation of Oligomerized Polyphrnol (Oligonol)"
Takehito Miura (Amino Up Chemical Co., Ltd., Japan), FOOD STYLE 21, 209: 71-74, 2014

52. "Effect of Lychee Fruit Extract (Oligonol) on Peripheral Circulation, a Pilot Study"
Kohei Homma (Amino Up Chemical Co., Ltd., Japan), Natural Medicine Journal, 6(7), 2014

51. "Oligonol Supplementation Affects Leukocyte and Immune Cell Counts after Heat Loading in Humans"
Jeong Beom Lee (Soonchunhyang University, Korea), Nutrients, 6(6), 2466-2477, 2014

50. "Oligonol, a Low-Molecular-Weight Polyphenol Derived from Lychee Fruit, Attenuates Diabetes-Induced Renal Damage through the Advanced Glycation End Product-Related Pathway in db/db Mice"
Chan Hum Park (Daegu Haany University, Korea), The Journal of Nutrition, 114, 193961, 2014

49. "Suppression of N-Methyl-N-Nitrosourea-Induced Retinal Damage in Mice by Oligonol, an Oligomerized Polyphenol Formulation"
Satoru Yui (Teikyo University, Japan), Advances in Biological Chemistry, 4, 138-147, 2014

48. "The Anti-inflammatory Effects of Flavanol-rich Lychee Fruit Extract in Rat Hepatocytes"
Mikio Nishizawa (Ritsumeikan University, Japan), PLOS ONE, 9(4), e93818, 2014

47. "Thirteen-week oral dose toxicity study of Oligonol containing oligomerized polyphenols extracted from lychee and green tea"
Kentaro Kitadate (Amino Up Chemical Co., Ltd., Japan), Regulatory Toxicology and Pharmacology, 68: 140-146, 2014

・2013

46. "Oligonol Inhibits Dextran Sulfate Sodium-Induced Colitis and Colonic Adenoma Formation in Mice"
Young-Joon Surh (Seoul National University, Korea), Antioxidants & Redox Signaling, 19(2): 102-114, 2013

45. "Oligomerized lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress in neuronal cells"
Hideki Ono (Kyorin University, Japan), British Journal of Nutrition, 28: 1-10, 2013

44. "Analysis of supercooling activity of tannin-related polyphenols"
Seizo Fujikawa (Hokkaido University, Japan), Cryobiology, 67: 40-49, 2013

43. "Oligonol Supplementation Attenuates Body Temperature and the Circulating Levels of Prostaglandin E2 and Cyclooxygenase-2 After Heat Stress in Humans"
Jeong Beom Lee (Soonchunhyang University, Korea), Journal of Medical Food, 16(4): 318-323, 2013

42. "Functional Analyses of Oligonol by Novel Neutrophil Activity Measurement System"
Katsuhiko Suzuki (Waseda University, Japan), Japanese Journal of Complementary and Alternative, 10(1): 59-62, 2013

・2012

41. "Safety of oligonol, a highly bioavailable lychee-derived polyphenolic antioxidant, on liver, kidney and heart function in rats"
Manashi Bagchi(NutriToday LLC, USA), Toxicology Mechanisms and Methods, 22(7): 555-559, 2012

40. "Oligonol-induced Degradation of Perilipin 1 is Regulated through Lysosomal Degradation Machinery"
Hideki Ohno (Kyorin University, Japan), Natural Product Communications, 7(9): 1193-1196, 2012

39. "Oligomerized lychee fruit extract (OLFE) and a mixture of vitamin C and vitamin E for endurance capacity in a double blind randomized controlled trial"
Seung Wan Kang (Seoul National University, Korea), Journal of Clinical Biochemistry and Nutrition, 50(2): 106-113, 2012

・2011

38. "Effect of Oligonol Intake on Cortisol and Cytokines, and Body Temperature after Leg Immersion into Hot Water"
Jeong-Beom Lee (Soonchunhyang University, Korea), Food Science Biotechnology, 20(3): 659-663, 2011

37. "The Function of the Next Generation of Oligomerized Polyphrnol (Oligonol)"
Koji Wakame (Amino Up Chemical Co., Ltd., Japan), aromatopia (Japanese), 20(4): 87-91, 2011

36. "Treatment with oligonol, a low-molecular polyphenol derived from lychee fruit, attenuates diabetes-induced hepatic damage through regulation of oxidative stress and lipid metabolism"
Takako Yokozawa (University of Toyama, Japan), British Journal of Nutrition, 106: 1013-1022, 2011

35. "Antioxidant Therapy as a Potential Approach to Severe Influenza-Associated Complications"
Hiroo Toyoda (Tokyo University of Pharmacy and Life Sciences, Japan), Molecules, 16: 2032-2052, 2011

34. "Absorption of Nitrogen Dioxide by the Polyphenol Solution"
Eiji Obata (Muroran Institute of Technology, Japan), KAKORONBUNSHU, 37(2): 162-166, 2011

33. "Effects of Oligonol®, an oligomerized polyphenol formulated from lychee fruit, on serum concentration and urinary excretion of uric acid"
Yuji Moriwaki (Hyogo College of Medicine, Japan), Journal Journal of Functional Foods, 3, 13-16, 2011

32. "The Function of the Next Generation of Polyphrnol "Oligonol""
Jun Takanari (Amino Up Chemical Co., Ltd., Japan), New Food Industry, 53(3), 9-21, 2011

31. "Evaluation of the formula designed as drink containing several natural nutrition in the human sex enhancement"
Hiroyoshi Moriyama (Showa Pharmaceutical University, Japan), FOOD STYLE 21, 165, 41-43, 2011

30. "Supplementation with a Flavanol-rich Lychee Fruit Extract Influences the Inflammatory Status of Young Athletes"
Mikio Nishizawa (Ritsumeikan University, Japan), Phytotherapy Research, 25(10): 1486-1493, 2011

・2010

29. "Oxidative Stress in Hypobaric and Normobaric Hypoxia and Antioxidant effect of Oligonol"
Jun-ichi Nagasawa (The University of Electro-Communications, Japan), Japanese Journal of Mountain Medicine, 30, 118-124, 2010

28. "Comparison of the Effect of Oligonol, A New Lychee Fruit-derived Low Molecular Form of Polyphenol, and Epigallocatechin-3-gallate on Lipolysis in Rat Primary Adipocytes"
Jun-etsu Ogasawara (Kyorin University, Japan), Phytotherapy Research, DOI: 10.1002/ptr.3296, 2010

27. "Oligonol, an oligomerized lychee fruit-derived polyphenol, activates the Ras/ Raf-1/ MEK1/2 cascade independent of the IL-6 signaling pathway in rat primary adipocytes"
Jun-etsu Ogasawara (Kyorin University, Japan), Biochemical and Biophysical Research Communications, 402, 554-559, 2010

26. "The effect of Oligonol intake on cortisol and related cytokines in healthy young men"
Hun-Mo Yanga (Soonchunhyang University, Korea), Nutrition Research and Practice, 4(3), 203-207, 2010

25. "Hypolipidaemic and antioxidative effects of oligonol, a low-molecular-weight polyphenol derived from lychee fruit, on renal damage in type 2 diabetic mice"
Takako Yokozawa (University of Toyama, Japan), British Journal of Nutrition, 104(8), 1120-1128, 2010

24. "Oligonol a low molecular weight polyphenol of lychee fruit extract inhibits proliferation of influenza virus by blocking reactive oxygen species-dependent ERK phosphorylation"
Mehran Haidari (The University of Texas Health Science Center at Houston, USA), Phytomedicine, 17(13), 1047-1056, 2010

23. "Therapeutic Effect of Oligonol, a Low-molecular Polyphenol Formulation Derived from Lychee Fruits on Murine Oral Candidiasis"
Shigeru Abe (Institute of Medical Mycology, Teikyo University, Japan), Japanese Journal of Medical Mycology, 51(2), 137-142, 2010

22. "The Function of the Next Generation Polyphenol, "Oligonol""
Takehito Miura (Amino Up Chemical Co. Ltd., Japan), Biotechnology in Functional Foods and Nutraceuticals (Taylor & Francis), 91-101, 2010

21. "Bioactivity of a flavanol-rich lychee fruit extract in adipocytes and its effects on oxidant defense and indices of metabolic syndrome in animal models"
Carl L. Keen (University of California, Davis, USA), Phytotherapy Research, 24, 1223-1228, 2010

20. "Beneficial effect of the oligomerized polyphenol oligonol on high glucose-induced changes in eNOS phosphorylation and dephosphorylation in endothelial cells"
Hiroki Yokoo (University of Toyama, Japan), British Journal of Pharmacology, 159, 928-938, 2010

19. "The Function of the Next Generation of Polyphrnol "Oligonol""
Takehito Miura (Amino Up Chemical Co. Ltd., Japan), Japan Food Science, 49(1), 37-44, 2010

・2009

18. "Amelioration of abdominal obesity by low-molecular-weight polyphenol (Oligonol) from lychee"
Jun Nishihira (Hokkaido Information University, Japan), Journal of Functional Foods, 1(4), 341-348, 2009

17. "Oligonol, a new lychee fruit-derived low-molecular form of polyphenol, enhances lipolysis in primary rat adipocytes through activation of the ERK1/2 pathway"
Jun-etsu Ogasawara (Kyorin University, Japan), Phytotherapy Research 23, 1626-1633, 2009

16. "Inhibition of Lung Metastasis in Mice by Oligonol"
Hyung-In Moon, et al. (Wonkwang University, Korea), Phytotherapy Research, 23, 1043-1046, 2009

15. "Preventive Effects of Oligomerized Polyphenol on Estradiol-Induced Prostatitis in Rats"
Sung Joon Hong (Yonsei University College of Medicine, Korea), Yonsei Medical Journal, 50(3), 391-398, 2009

14. "Anti oxidative effects of Oligonol, new oligomerized polyphenol formulation"
Hideki Ono (Kyorin University, Japan), FOOD FUNCTION, 5(1), 2-7, 2009

13. "Oligonol, a lychee fruit-derived low molecular weight polyphenol formulation, inhibits UVB-induced cyclooxygenase-2 expression, and induces NAD(P)H: quinone oxidoreductase-1 expression in hairless mouse skin"
Joydeb Kumar Kundul (Seoul National University, South Korea), Journal of Functional Foods, 1, 98-108, 2009

・2008

12. "Inhibitory effects of oligonol on phorbol ester-induced tumor promotion and COX-2 expression in mouse skin: NF-κB and C/EBP as potential targets"
Joydeb Kumar Kundu, et al. (Seoul National University, South Korea), Cancer Letters, 273, 86-97, 2008

11. "The Function of the Next Generation of Polyphrnol "Oligonol""
Takehito Miura (Amino Up Chemical Co. Ltd., Japan), Japanese Journal of Complementary and Alternative Medicine, 5(3), 163-171, 2008

10. "Acute, subchronic and genotoxicity studies conducted with Oligonol, an oligomerized polyphenol formulated from lychee and green tea extracts"
Ashley Roberts, et al. (Cantox Health Sciences International, Canada), Food and Chemical Toxicology, 46, 3553-3562, 2008

9. "The Supplementation of Oligonol, the New Lychee Fruit-derived Polyphenol Converting into a Low-molecular Form, Has a Positive Effect on Fatigue during Regular Track-and-field Training in Young Athletes"
Hideki Ohno (Kyorin University, Japan), Advances in Exercise and Sports Physiology, 13(4), 93-99, 2008

8. "Anti oxidative effects of a new lychee fruitderived polyphenol mixture, Oligonol, converted into a low-molecular form in adipocytes"
Takuya Sakurai (Kyorin University, Japan), Biosci. Biotechnol. Biochem., 72(2), 463-476, 2008

7. "Oligonol Inhibits UVB-induced COX-2 Expression in HR-1 Hairless Mouse Skin ― AP-1 and C/EBP as Potential Upstream Targets"
Joydeb Kumar Kundu (Seoul National University, South Korea), Photochemistry and Photobiology, 84, 399-406, 2008

6. "Flavanols: digestion, absorption and bioactivity"
Robert M. Hackman, et al. (University of California, Davis, USA), Phytochemistry Reviews, 7, 195-208, 2008

・2007

5. "Production of Oligomeric Proanthocyanidins by Fragmentation of Polymers"
Gen-ichiro Nonaka (Usaien Pharmaceutical Co. Ltd., Japan), Japanese Journal of Food Chemistry, 14(3), 134-139, 2007

4. "Significance of intake of antioxidant supplements in high-altitude climbing -Oligonol as a main subject-"
Hideki Ohno (Kyorin University, Japan), Japanese Journal of Mountain Medicine, 27, 43-60, 2007

3. "Modulation of infection-induced inflammation and locomotive deficit and longevity in senescence-accelerated mice-prone (SAMP8) model by the oligomerized polyphenol Oligonol"
Okeizie I. Aruoma (Touro University), Biomedicine & Pharmacotherapy, 61, 427-434, 2007

2. "Preparation, Characterization, and Antioxidative Effects of Oligomeric Proanthocyanidin-L-Cysteine Complexes"
Hajime Fujii (Amino Up Chemical Co. Ltd., Japan), Agricultural and Food Chemistry, 2007

・2006

1. "Evaluation of the safety and toxicity of the oligomerized polyphenol Oligonol"
Hajime Fujii (Amino Up Chemical Co. Ltd., Japan), Food and Chemical Toxicology, 45, 378-387, 2006

 

(c)2008 Oligonol-net All rights reserved. XHTML and CSS.